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Contaminants in Dietary Supplements: Toxicity, Doping Risk, and Current Regulation

2024/04/23 by Jesús Zapata-Linares, Guillermo Gervasini · 1 voice
Medicine · Biochemistry, Genetics and Molecular Biology · #Hormonal and reproductive studies #Muscle metabolism and nutrition #Pharmacology and Obesity Treatment

paper · doi:10.1123/ijsnem.2023-0263

openalex publication_date 2024/04/23 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/16

Abstract

Athletes, both amateur and professional, often resort to the consumption of nutritional supplements without professional supervision and without being aware of the risks they may entail. We conducted an exhaustive literature search to determine the most common substances found as contaminants in dietary supplements. For each substance, we analyzed its mechanism of action, clinical indication, health risk, and putative use as doping agent. In addition, we evaluated the current regulation of these supplements. Contamination of nutritional supplements (accidental or intentional), especially with steroids and stimulants, is a hazardous situation. The prolonged consumption of these products without being aware of their composition can cause serious health risks and, in the case of professional athletes, a possible sanction for doping.

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