DNA mismatch and damage patterns revealed by single-molecule sequencing

2024/06/12 by Mei Hong Liu, Benjamin M. Costa, Emilia C. Bianchini +24 · 1 voice
Biochemistry, Genetics and Molecular Biology · Medicine · #Cancer Genomics and Diagnostics #DNA Repair Mechanisms #Genetic factors in colorectal cancer

paper · doi:10.1038/s41586-024-07532-8

crossref issued 2024/06/12 · crossref published 2024/06/12 · crossref published-online 2024/06/12 · openalex publication_date 2024/06/12 · crossref created 2024/06/12 · crossref published-print 2024/06/20 · crossref deposited 2024/06/24 · openalex created_date 2025/10/10 · crossref indexed 2026/08/01 · openalex updated_date 2026/08/04

Citations

• Umap and Bismap: quantifying genome and methylome mappability
• The repertoire of mutational signatures in human cancer
• The mutational constraint spectrum quantified from variation in 141,456 humans
• Twelve years of SAMtools and BCFtools
• The complete sequence of a human genome
• A draft human pangenome reference

Discussions

• ‘Vaccines cause autism’ is debunked but evidence that old sperm accumulate mutations is ignored. Most recently most accurately detected below, Fig 4. [bsky, 0 points, 0 comments]