2023/12/01 by Joanna Dong, Eugene M. Helveston, C William Hanke · 1 voice
Medicine · #Botulinum Toxin and Related Neurological Disorders #Cancer Treatment and Pharmacology #Neurological disorders and treatments
paper · doi:10.36849/jdd.7288
openalex publication_date 2023/12/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/31
The history of botulinum toxin dates back to the late 1700s, when food preparation, storage, and later canning practices led to outbreaks of botulism across Europe and the United States. It is from these initial incidents that the remarkable discovery of botulinum toxin was eventually made, sparking over 200 years of further scientific inquiry and medical innovation. To date, 6 botulinum toxin products have been commercialized in North America with numerous indications across the specialties of ophthalmology, neurology, urology, dermatology, plastic surgery, and otolaryngology. This article traces the key moments and important players in the remarkable journey of this biologic poison and wonder drug. J Drugs Dermatol. 2024;23(1) doi:10.36849/JDD.7288.