Nickel-catalyzed dynamic kinetic cross-electrophile coupling of benzylic alcohols and alkenyl triflates

2023/11/13 by Xuejing Peng, Jingxian Huang, Guanyu Han +1 · 1 voice
Chemistry · #Catalytic Cross-Coupling Reactions #Catalytic C–H Functionalization Methods #Asymmetric Hydrogenation and Catalysis

paper · pdf · doi:10.1039/d3qo01416a

openalex publication_date 2023/11/13 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/16

Abstract

We report a dynamic kinetic cross-electrophile coupling reaction of benzylic alcohols with alkenyl triflates. The reaction enables replacement of the alcohol group with an alkenyl functionality, yielding versatile benzyl-substituted cyclic alkenes.

Citations

• Nickel-Catalyzed Enantioselective Reductive Cross-Coupling Reactions
• Cross-Electrophile Couplings of Activated and Sterically Hindered Halides and Alcohol Derivatives
• Metallaphotoredox-enabled deoxygenative arylation of alcohols

Discussions

• 🏆We are happy to present another OCF Outstanding paper by Xing-Zhong Shu et al. Congratulations to the authors! 👉Nickel-catalyzed dynamic kinetic cross-electrophile coupling of benzylic alcohols an [bsky, 0 points, 0 comments]

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