Appendicectomy plus standard medical therapy versus standard medical therapy alone for maintenance of remission in ulcerative colitis (ACCURE): a pragmatic, open-label, international, randomised trial

2025/04/11 by Yair I Z Acherman, Yaïr I. Z. Acherman, Naila Arebi +94 · 1 voice
Biochemistry, Genetics and Molecular Biology · Medicine · #Appendicitis Diagnosis and Management #Diagnosis and treatment of tuberculosis #Inflammatory Bowel Disease

paper · doi:10.1016/s2468-1253(25)00026-3

openalex created_date 2025/04/11 · openalex publication_date 2025/04/11 · crossref created 2025/04/11 · crossref deposited 2025/05/10 · crossref issued 2025/06/01 · crossref published 2025/06/01 · crossref published-print 2025/06/01 · crossref indexed 2026/07/31 · openalex updated_date 2026/08/02

Citations

• Classification of Surgical Complications
• The European Organization for Research and Treatment of Cancer QLQ-C30: A Quality-of-Life Instrument for Use in International Clinical Trials in Oncology
• STRIDE-II: An Update on the Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) Initiative of the International Organization for the Study of IBD (IOIBD): Determining Therapeutic Goals for Treat-to-Target strategies in IBD
• Ulcerative colitis

Discussions

• 💥 Implications Appendicectomy may be: ✅ Effective ✅ Safe ✅ Cost-saving (↓ biologic use) 🛠️ A valuable adjunct in select UC patients First RCT to prove this. Bold step toward rethinking #ulcerativec [bsky, 0 points, 1 comments]