Asymmetric [4 + 3] cycloaddition of hydroxyphenyl indolinones to synthesize novel spirooxindoles

2025/01/01 by Shuhui Huang, Yongquan Xu, Mohan Li +2 · 1 voice
Chemistry · Pharmacology, Toxicology and Pharmaceutics · #Asymmetric Synthesis and Catalysis #Fluorine in Organic Chemistry #Oxidative Organic Chemistry Reactions

paper · doi:10.1039/d5qo00075k

openalex publication_date 2025/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/02

Abstract

The first asymmetric [4 + 3] cycloaddition of hydroxyphenyl indolinones has been reported to afford spirooxindole oxadiazepines in high yields with excellent stereoselectivities, which is a new class of seven-membered spirooxindole compounds.

Discussions

• 👉Check out the back cover of Organic Chemistry Frontiers issue 08 showcasing the research from Weiwu Ren et al. 🔊Asymmetric [4 + 3] cycloaddition of hydroxyphenyl indolinones to synthesize novel sp [bsky, 0 points, 0 comments]

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