The next 10 years of behavioural genomic research

2022/11/04 by Robert Plomin · 1 voice
Biochemistry, Genetics and Molecular Biology · #Genetic Associations and Epidemiology #Genetic Mapping and Diversity in Plants and Animals #Receptor Mechanisms and Signaling

paper · pdf · doi:10.1002/jcv2.12112

openalex publication_date 2022/11/04 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01

Abstract

Abstract Background The explosion caused by the fusion of quantitative genetics and molecular genetics will transform behavioural genetic research in child and adolescent psychology and psychiatry. Methods Although the fallout has not yet settled, the goal of this paper is to predict the next 10 years of research in what could be called behavioural genomics . Results I focus on three research directions: the genetic architecture of psychopathology, causal modelling of gene‐environment interplay, and the use of DNA as an early warning system. Conclusion Eventually, whole‐genome sequencing will be available for all newborns, which means that behavioural genomics could potentially be applied ubiquitously in research and clinical practice.

Citations

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• Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction
• Mapping genomic loci implicates genes and synaptic biology in schizophrenia
• Mother's and children's ADHD genetic risk, household chaos and children's ADHD symptoms: A gene–environment correlation study

Discussions

• Whatever you or I believe doesn't matter in the grand scheme of it all. What matters is who the research funding comes from, and who receives it. This paper goes into a bit of explanation of how thing [bsky, 0 points, 1 comments]

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