Cu-catalyzed regiodivergent and stereoselective silylation of 2,3-disubstituted 1,3-dienes

2025/01/01 by Ziwei Luo, Zeng Chuan Hao, Junyang Cen +3 · 1 voice
Chemistry · #Asymmetric Hydrogenation and Catalysis #Catalytic Cross-Coupling Reactions #Catalytic C–H Functionalization Methods

paper · doi:10.1039/d5qo00512d

openalex publication_date 2025/01/01 · openalex created_date 2025/05/07 · openalex updated_date 2026/07/13

Abstract

A method involving Cu-catalyzed regiodivergent and stereoselective silylation of 2,3-disubstituted 1,3-dienes is developed, delivering 2,1-, 4,1-protosilylation and 4,1-borosilylation products with high levels of scope, scalability and practicality.

Citations

• Asymmetric synthesis of allylic compounds via hydrofunctionalisation and difunctionalisation of dienes, allenes, and alkynes

Discussions

• 📢Check out recent research regarding #regiodivergent #silylation of conjugated dienes to access diverse #organosilicon compounds 👉Cu-catalyzed regiodivergent and stereoselective silylation of 2,3-d [bsky, 0 points, 0 comments]

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