Oxetane as a part of modern medicinal chemistry toolbox: the advanced synthesis of 3,3-disubstituted building blocks

2025/01/01 by Eduard Litskan, Oleksandr V. Semenchenko, Serhii Lynnyk +8 · 1 voice
Biochemistry, Genetics and Molecular Biology · Pharmacology, Toxicology and Pharmaceutics · #Chemical Reactions and Isotopes #bioluminescence and chemiluminescence research

paper · doi:10.1039/d5qo00572h

openalex publication_date 2025/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/06/11

Abstract

Despite numerous potential advantages of oxetanes, their restricted synthetic accessibility and propensity to ring-opening hamper their wide application in drug design. In this research, we have shown our solutions for this problem.

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