Sleep Spindle Abnormalities as Neurophysiological Biomarkers of Schizophrenia Spectrum Disorders: From Cellular Mechanisms and Neural Circuits to Clinical Implications

2025/06/25 by Anna Castelnovo, Armando D’Agostino, Ahmad Mayeli +3 · 1 voice
Neuroscience · Psychology · #Regulation of Appetite and Obesity #Sleep and Wakefulness Research #Sleep and related disorders

paper · doi:10.1016/j.biopsych.2025.06.014

openalex publication_date 2025/06/25 · crossref created 2025/06/25 · openalex created_date 2025/10/10 · crossref issued 2025/12/01 · crossref published 2025/12/01 · crossref published-print 2025/12/01 · crossref deposited 2026/05/09 · crossref indexed 2026/07/27 · openalex updated_date 2026/08/01

Citations

• Fast sleep spindle reduction in schizophrenia and healthy first-degree relatives: association with impaired cognitive function and potential intermediate phenotype
• Functional and structural abnormalities of thalamus in individuals at early stage of schizophrenia
• Sleep spindles as neurophysiological biomarkers of schizophrenia
• A single psychotomimetic dose of ketamine decreases thalamocortical spindles and delta oscillations in the sedated rat

Discussions

• Castelnovo et al., Biological Psychiatry, "Sleep spindle abnormalities as neurophysiological biomarkers of Schizophrenia spectrum disorders: From cellular mechanisms and neural circuits to clinical im [bsky, 0 points, 0 comments]