2020/11/19 by Bornali Datta, David Ford, Pinky Goyal +12 · 1 citation
Biochemistry, Genetics and Molecular Biology · Engineering · Medicine · #Bacterial Identification and Susceptibility Testing #Biosensors and Analytical Detection #Tuberculosis Research and Epidemiology
paper · doi:10.1093/trstmh/traa152
openalex publication_date 2020/11/19 · crossref created 2020/11/19 · crossref issued 2020/12/21 · crossref published 2020/12/21 · crossref published-online 2020/12/21 · crossref published-print 2021/08/02 · crossref deposited 2021/08/02 · openalex created_date 2025/10/10 · crossref indexed 2026/07/30 · openalex updated_date 2026/07/31
BACKGROUND: There is no experience of point-of-care (POC) microbiological confirmation for TB in India in field settings. METHODS: Under the TB-Free Haryana project, a mobile van-mounted digital x-ray and portable GeneXpert system screened all presumptive TB patients with strong clinic-radiological suspicion for TB. RESULTS: Of 1673 x-rays, 215 (13%) had findings suggestive of TB, 109 had strong clinical suspicion and were eligible for POC GeneXpert, in whom a test was performed in 82 (75%) cases; 59 (72%) tested positive and were initiated on treatment within 24 h. CONCLUSIONS: A mobile van equipped with digital x-ray and POC GeneXpert is feasible and has a good success rate with potential for replication.