2009/02/24 by Sara Chandy, Kumiko Yoshimatsu, Hari Kishan Boorugu +6
Environmental Science · Medicine · #Fire effects on ecosystems #Viral Infections and Outbreaks Research #Viral Infections and Vectors
paper · doi:10.1016/j.trstmh.2009.01.016
openalex publication_date 2009/02/24 · crossref created 2009/02/24 · crossref issued 2009/04/01 · crossref published 2009/04/01 · crossref published-print 2009/04/01 · crossref deposited 2020/05/16 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01 · crossref indexed 2026/08/01
Study of hantavirus infections in India is in its early stages. As early symptoms of hantavirus disease can be non-specific and the diagnosis confirmed only by laboratory testing, use of appropriate diagnostic tools is important. To improve the diagnosis of hantavirus infections in India, commercial ELISA systems followed by indirect immunofluorescence assays were used to detect anti-hantavirus IgM and IgG in samples from patients with acute febrile illness. Of 347 patients tested, 5.2% showed serological evidence of hantavirus infection. Sequences obtained from patients showing molecular evidence of hantavirus infection were related to Hantaan virus. In the absence of mu-capture ELISA, we recommend the use of combination testing systems in areas non-endemic for hantavirus infections. In India there is an increased risk of rodent-borne infections and the differential diagnosis of undifferentiated febrile illness should include hantavirus infection.