A silicon probe with integrated microheaters for thermal marking and monitoring of neural tissue

1997/01/01 by Jingkuang Chen, K.D. Wise
Neuroscience · Engineering · #Neuroscience and Neural Engineering #3D Printing in Biomedical Research #CCD and CMOS Imaging Sensors

paper · doi:10.1109/10.605437

Abstract

This paper describes a microheater structure and its integration on a silicon microprobe. The 30-micron-diameter microstructure can be used to heat local areas of tissue or to measure local tissue temperature with an accuracy of < 0.3 degree C. The polysilicon microheater is suspended on a dielectric membrane to reduce undesired heat conduction to the probe substrate. The heating efficiency is 4.4 degrees C/mW in still water and 2.2 degrees C/mW in guinea pig cortex. Six milliwatts applied for 2 min in cortex produces a temperature of 50 degrees C, creating a well-defined 50-micron-wide lesion for determining probe position histologically. Fabrication of the heaters requires no additional masking or processing steps in addition to those normally used for recording or stimulating probes.

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