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Lymphoscintigraphy for the diagnosis of extremity lymphedema: Current controversies regarding protocol, interpretation, and clinical application

2019/06/18 by Marco Pappalardo, Ming‐Huei Cheng · 1 citation
Medicine · #Diagnosis and Treatment of Venous Diseases #Lymphatic Disorders and Treatments #Lymphatic System and Diseases

paper · doi:10.1002/jso.25526

crossref issued 2019/06/18 · crossref published 2019/06/18 · crossref published-online 2019/06/18 · openalex publication_date 2019/06/18 · crossref created 2019/06/18 · crossref published-print 2020/01/01 · crossref deposited 2023/09/08 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29 · crossref indexed 2026/07/31

Abstract

Appropriate diagnosis, staging and a further selection of the best treatment are fundamental for the management of patients with extremity lymphedema. Several clinical and imaging tools have been described for these purposes. Lymphoscintigraphy is still considered the gold standard imaging modality for diagnosing lymphedema. However, protocol variability and poor image resolution can make the interpretation challenging. Here, we reviewed technical aspects of lymphoscintigraphy, interpretation of the lymphoscintigraphy findings, staging, and its clinical application.

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