The clinical use of indocyanine green as a near‐infrared fluorescent contrast agent for image‐guided oncologic surgery

2011/04/14 by Boudewijn E. Schaafsma, J. Sven D. Mieog, Merlijn Hutteman +7 · 1 citation
Engineering · Medicine · #Colorectal Cancer Surgical Treatments #Nanoplatforms for cancer theranostics #Surgical Simulation and Training

paper · doi:10.1002/jso.21943

crossref issued 2011/04/14 · crossref published 2011/04/14 · crossref published-online 2011/04/14 · openalex publication_date 2011/04/14 · crossref created 2011/04/14 · crossref published-print 2011/09/01 · crossref deposited 2023/10/10 · openalex created_date 2025/10/10 · crossref indexed 2026/08/01 · openalex updated_date 2026/08/02

Abstract

Optical imaging using near-infrared (NIR) fluorescence provides new prospects for general and oncologic surgery. ICG is currently utilised in NIR fluorescence cancer-related surgery for three indications: sentinel lymph node (SLN) mapping, intraoperative identification of solid tumours, and angiography during reconstructive surgery. Therefore, understanding its advantages and limitations is of significant importance. Although non-targeted and non-conjugatable, ICG appears to be laying the foundation for more widespread use of NIR fluorescence-guided surgery.

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