mRNA therapeutics beyond vaccines: dosing precision challenges and clinical translation framework

2025/10/22 by Sarfaraz K. Niazi · 1 voice
Biochemistry, Genetics and Molecular Biology · Medicine · #RNA Interference and Gene Delivery #Virus-based gene therapy research #CAR-T cell therapy research

paper · pdf · doi:10.1039/d5pm00159e

openalex publication_date 2025/10/22 · openalex created_date 2025/10/24 · openalex updated_date 2026/07/31

Abstract

Messenger RNA (mRNA) therapeutics have emerged as a transformative platform following the success of COVID-19 vaccines.

Citations

• The expanding regulatory mechanisms and cellular functions of circular RNAs
• Engineering precision nanoparticles for drug delivery
• Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine
• Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine
• mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability
• CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis
• Human organs-on-chips for disease modelling, drug development and personalized medicine
• Chemistry and Biology of Self-Cleaving Ribozymes

Discussions

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