Identification and Validation of SLC9A2 as A Potential Tumor Suppressor in Colorectal Cancer: Integrating Bioinformatics Analysis with Experimental Confirmation

2024/05/29 by Yanmin Liu, Yan-min Liu, Tie-cheng Yang +16 · 1 voice
Biochemistry, Genetics and Molecular Biology · Medicine · #Bioinformatics and Genomic Networks #Biology #Cancer #Cancer research #Colorectal cancer #Computational biology #Ferroptosis and cancer prognosis #Gene #Gene expression #Gene expression profiling #Genetics #Genomics and Rare Diseases #KEGG #Transcriptome

paper · doi:10.1007/s11596-024-2871-5

crossref issued 2024/05/29 · crossref published 2024/05/29 · crossref published-online 2024/05/29 · openalex publication_date 2024/05/29 · crossref created 2024/05/29 · crossref published-print 2024/06/01 · crossref deposited 2024/06/28 · openalex created_date 2025/10/10 · crossref indexed 2026/03/27 · openalex updated_date 2026/07/23

Citations

• TIMER: A Web Server for Comprehensive Analysis of Tumor-Infiltrating Immune Cells
• Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
• Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
• Tissue-based map of the human proteome
• Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction Networks
• GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses

Discussions

• Bioinformatic and experimental analyses reveal #SLC9A2 as a #TumorSuppressor in #ColorectalCancer, inhibiting proliferation and metastasis via #MAPK signaling, highlighting its potential as a diagnost [bsky, 0 points, 0 comments]