Nanoparticle-delivered miR-486-5p inhibits H 2 O 2 -induced injury in cultured endothelial and kidney tubular epithelial cells

2025/12/15 by Ali Maadelat, Savindi Wehella, Adrianna Douvris +3 · 1 voice
Biochemistry, Genetics and Molecular Biology · Medicine · #MicroRNA in disease regulation #Inflammasome and immune disorders #Chemotherapy-induced organ toxicity mitigation

paper · pdf · doi:10.1039/d5na00581g

openalex created_date 2025/12/15 · openalex publication_date 2025/12/15 · openalex updated_date 2026/08/01

Abstract

miR-486-5p nanoparticles protect kidney cells in an in vitro AKI injury model and have the potential to develop miRNA-based nanotherapies for AKI applications.

Citations

• The endothelial cell in ischemic acute kidney injury: implications for acute and chronic function
• Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Discussions

• Have you seen the back cover of Nanoscale Advances issue 4? 'Nanoparticle-delivered miR-486-5p inhibits H2O2-induced injury in cultured endothelial and kidney tubular epithelial cells' by Kevin D. Bur [bsky, 0 points, 0 comments]

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