ESE-1 Regulates CREB-Mediated PTEN Expression to Activate the PI3K/Akt Pathway and Promote High-Glucose-Induced Endothelial Cell Injury

2025/09/16 by Tao Liu, Jian-jun Hu · 1 voice
Biochemistry, Genetics and Molecular Biology · Medicine · #Angiogenesis and VEGF in Cancer #Cell Adhesion Molecules Research #PI3K/AKT/mTOR signaling in cancer

paper · doi:10.1007/s11596-025-00105-4

crossref issued 2025/09/16 · crossref published 2025/09/16 · crossref published-online 2025/09/16 · openalex publication_date 2025/09/16 · crossref created 2025/09/16 · crossref published-print 2025/10/01 · openalex created_date 2025/10/10 · crossref deposited 2025/11/04 · crossref indexed 2025/11/04 · openalex updated_date 2026/07/23

Citations

• ICAM-1 and VCAM-1: Gatekeepers in various inflammatory and cardiovascular disorders

Discussions

• This study demonstrates that ESE-1 regulates #CREB-mediated #PTEN expression, thereby activating #PI3K/AKT signaling in #Endothelial cells, influencing #OxidativeStress, #Inflammation, and #adhesion u [bsky, 0 points, 0 comments]