PAR-1 in Alzheimer’s Disease: Pathophysiological Insights and Mechanistic Perspectives

2026/03/05 by Neha, Snehashis Mandal, Vipual Sharma +2 · 1 voice
Biochemistry, Genetics and Molecular Biology · Medicine · #Alzheimer's disease research and treatments #Blood Coagulation and Thrombosis Mechanisms #Protease and Inhibitor Mechanisms

paper · doi:10.1007/s11596-026-00175-y

crossref issued 2026/03/05 · crossref published 2026/03/05 · crossref published-online 2026/03/05 · openalex publication_date 2026/03/05 · crossref created 2026/03/05 · openalex created_date 2026/03/06 · crossref published-print 2026/04/01 · crossref deposited 2026/04/28 · crossref indexed 2026/04/29 · openalex updated_date 2026/07/29

Citations

• Protease-activated receptors (PARs): mechanisms of action and potential therapeutic modulators in PAR-driven inflammatory diseases
• Inflammation and tumor progression: signaling pathways and targeted intervention

Discussions

• This review highlights roles of #PAR1 in Aβ deposition, #Neuroinflammation, and #TauPathology in #Alzheimersdisease, while discussing #therapeutic opportunities such as repurposing PAR 1 #inhibitors a [bsky, 0 points, 0 comments]