2025/11/15 by Mathias Eerens, Kasper Hermans · 1 voice
Biochemistry, Genetics and Molecular Biology · #Congenital limb and hand anomalies #Connective tissue disorders research #TGF-β signaling in diseases
paper · pdf · doi:10.3899/jrheum.2025-0777
openalex created_date 2025/11/15 · openalex publication_date 2025/11/15 · openalex updated_date 2026/08/01
Tarsal-carpal coalition syndrome (TCC) is a rare autosomal dominant inherited disorder characterized by progressive synostosis of the tarsals, carpals, and phalanges with wide phenotypic variation.<sup>1</sup> A 25-year-old male individual presented at the rheumatology clinic with a 1-year history of peripheral joint pain.