2026/01/01 by D. Zamudio, Livia Gisbert, G. Egea +2 · 1 voice
Medicine · #Anesthesia and Pain Management #Pain Management and Opioid Use #Pediatric Pain Management Techniques
paper · doi:10.1002/anr3.70050
openalex publication_date 2026/01/01 · openalex created_date 2026/01/25 · openalex updated_date 2026/05/21
Summary Continuous wound infusion with local anaesthetics after open abdominal surgery may provide opioid‐sparing analgesia, but evidence on very low‐concentration regimens is limited. We conducted a prospective observational study including 50 patients receiving continuous infusion of levobupivacaine 0.0625% via pre‐peritoneal or subfascial catheters at a flow rate of 12 ml.h −1 per catheter. Six patients (12%) required intravenous morphine rescue in the first 48 h, with a median dose of 3 mg. Median pain scores remained consistently low and 14 patients (28%) received additional local anaesthetic boluses with effective relief. No major catheter‐related complications or systemic local anaesthetic toxicity were observed. Continuous wound infusion with levobupivacaine 0.0625% after open abdominal surgery was feasible and associated with minimal opioid use. These findings provide preliminary evidence supporting the feasibility of an ultralow concentration regimen.