Fast and selective protein modification with iron-substituted polyoxometalates <i>via</i> a radical pathway

2025/01/01 by Mhamad Aly Moussawi, Shorok A. M. Abdelhameed, Francisco de Azambuja +4 · 1 voice
Materials Science · Chemistry · #Polyoxometalates: Synthesis and Applications #Metal-Organic Frameworks: Synthesis and Applications #biodegradable polymer synthesis and properties

paper · pdf · doi:10.1039/d5qi01454a

openalex publication_date 2025/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/02

Abstract

Leveraging the Lewis acidity and redox activity of Fe-substituted polyoxometalate clusters facilitates the regioselective hydrolytic (slow) or oxidative (fast) cleavage of proteins near their binding sites.

Citations

• Catalytic Decomposition of Hydrogen Peroxide by Fe(III) in Homogeneous Aqueous Solution: Mechanism and Kinetic Modeling
• ROS in cancer therapy: the bright side of the moon

Discussions

• 👉𝐅𝐚𝐬𝐭 𝐚𝐧𝐝 𝐬𝐞𝐥𝐞𝐜𝐭𝐢𝐯𝐞 𝐩𝐫𝐨𝐭𝐞𝐢𝐧 𝐦𝐨𝐝𝐢𝐟𝐢𝐜𝐚𝐭𝐢𝐨𝐧 𝐰𝐢𝐭𝐡 𝐢𝐫𝐨𝐧-𝐬𝐮𝐛𝐬𝐭𝐢𝐭𝐮𝐭𝐞𝐝 𝐩𝐨𝐥𝐲𝐨𝐱𝐨𝐦𝐞𝐭𝐚𝐥𝐚𝐭𝐞𝐬 𝐯𝐢𝐚 𝐚 𝐫𝐚𝐝𝐢𝐜𝐚𝐥 𝐩𝐚𝐭𝐡𝐰𝐚𝐲 by Tatjan [bsky, 0 points, 0 comments]