2004/01/21 by Masayoshi Murakami, Satoshi Watanabe, Tsuyoshi Inoue +1
Engineering · Neuroscience · #Advanced Chemical Sensor Technologies #Neurobiology and Insect Physiology Research #Olfactory and Sensory Function Studies
paper · doi:10.1002/neu.10295
crossref issued 2004/01/21 · crossref published 2004/01/21 · crossref published-online 2004/01/21 · openalex publication_date 2004/01/21 · crossref created 2004/01/26 · crossref published-print 2004/02/15 · crossref deposited 2023/10/07 · openalex created_date 2025/10/10 · openalex updated_date 2026/05/21 · crossref indexed 2026/07/27
The procerebrum (PC) of the terrestrial mollusk Limax is a highly developed second-order olfactory center consisting of two electrophysiologically distinct populations of neurons: nonbursting (NB) and bursting (B). NB neurons are by far the more numerous of the two cell types. They receive direct synaptic inputs from afferent fibers from the tentacle ganglion, the primary olfactory center, and also receive periodic inhibitory postsynaptic potentials (IPSPs) from B neurons. Odor-evoked activity in the NB neurons was examined using perforated patch recordings. Stimulation of the superior tentacle with odorants resulted in inhibitory responses in 45% of NB neurons, while 11% of NB neurons showed an excitatory response. The specific response was reproducible in each neuron to the same odorant, suggesting the possibility that activity of NB neurons may encode odor identity. Analysis of the cycle-averaged membrane potential of NB neurons revealed a correlation between the firing rate and the membrane potential at the plateau phase between IPSPs. Also, the firing rate of NB neurons was affected by the frequency of the IPSPs. These results indicate the existence of two distinct mechanisms for the regulation of NB neuron activity.