Conserved and distinct expression of circular RNAs in commercially used Marek’s disease vaccine viruses

2025/09/05 by Camille Ponsard, Alexis S. Chasseur, Pierre Lombard +8 · 1 voice
Biochemistry, Genetics and Molecular Biology · Agricultural and Biological Sciences · Medicine · #Circular RNAs in diseases #Animal Virus Infections Studies #Viral Infections and Immunology Research

paper · doi:10.1099/jgv.0.002146

openalex publication_date 2025/09/05 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01

Abstract

between virulent and avirulent GaHV-2 strains. Our findings highlight a conserved pattern of virus-derived circRNAs in these related avian alphaherpesviruses. This conservation underscores the potential significance of these transcripts in completing the viral cycle and facilitating viral spread.

Citations

• Basic local alignment search tool
• History of the First-Generation Marek's Disease Vaccines: The Science and Little-Known Facts
• Natural RNA circles function as efficient microRNA sponges

Discussions

• Read the full paper here: doi.org/10.1099/jgv.... [bsky, 0 points, 0 comments]