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Rhythm Control and Risk Reduction: Evidence From a Narrative Review on Therapeutic Advances in Cardiac Arrhythmia Management

2025/12/15 by Saheed E. Sanyaolu, Omobolanle Ibukun Ogundele, Matthew O. Ogbe +6 · 1 voice
Medicine · #Cardiac electrophysiology and arrhythmias #Cardiovascular Syncope and Autonomic Disorders #Heart Rate Variability and Autonomic Control

paper · pdf · doi:10.70389/pjc.100014

openalex publication_date 2025/12/15 · openalex created_date 2025/12/21 · openalex updated_date 2026/07/31

Abstract

With the growing prevalence of cardiac arrhythmias, effective management is crucial to improve quality of life, reduce the risk of complications, and enhance survival rates. This narrative review aimed to comprehensively provide updates regarding the clinical management of cardiac arrhythmias. Lifestyle modifications, pharmacological interventions, and procedural therapies were identified to enhance cardiac rhythm and rate control, as well as address underlying comorbid factors. Lifestyle modalities included maintaining a healthy weight, ensuring an appropriate diet, exercising regularly, managing stress, and avoiding triggers like alcohol. However, uncertainty still persists regarding the harms or benefits of these foods rich in chocolate and caffeine. While lifestyle interventions are foundational, their effectiveness depends on disease severity and individualized treatment goals. Tailored strategies, including vagal maneuvers and genetics-guided therapy, offer promise for arrhythmia management. Recent advancements in therapies have also been uncovered, including the exploration of intranasal etripamil, inhaled flecainide, and cognitive behavioral therapy, which demonstrate potential for improved disease management. Minimally invasive technologies, including wearable monitors, robotic-assisted platforms, renal denervation, and procedures like the Maze technique and cardioneuroablation, are also being explored for reshaping arrhythmia treatment and recovery timelines. These innovations reinforce a personalized and data-driven framework for cardiovascular care and underscore the importance of integrating precision-based strategies to reduce arrhythmia burden, enhance treatment efficacy, and guide future research into safer and more targeted therapies.

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