2025/12/01 by J. B. Liu, Shuguang Lu, Juan Bao +14 · 1 voice
Environmental Science · Biochemistry, Genetics and Molecular Biology · #Bacteriophages and microbial interactions #Antibiotic Resistance in Bacteria #Infections and bacterial resistance
paper · pdf · doi:10.1002/mlf2.70042
openalex publication_date 2025/12/01 · openalex created_date 2025/12/26 · openalex updated_date 2026/07/23
Perinephric abscess, a common complication after kidney transplantation, often results from drug-resistant bacterial infections and is notoriously difficult to treat. Phage therapy has emerged as a promising alternative for such resistant infections. Here, we present two cases of perinephric abscesses in kidney transplant recipients (KTRs) treated with phage therapy. Our findings highlight the need for personalized treatment plans and timely intervention with phage therapy to improve patient outcomes. Future research should focus on overcoming barriers like biofilms to make this treatment more effective. Ultimately, phage therapy could lead to better survival rates and improved quality of life for transplant patients facing severe infections. This study is a step forward in the fight against superbugs, offering a potential alternative when antibiotics fail.