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New Triterpenes from Gymnema sylvestre

2013/06/01 by Armando Zarrelli, Marina DellaGreca, Afef Ladhari +2 · 2 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Natural product bioactivities and synthesis #Plant biochemistry and biosynthesis #Natural Antidiabetic Agents Studies

paper · doi:10.1002/hlca.201200331

Abstract

Abstract Phytochemical investigation of the aerial parts of Gymnema sylvestre has led to the isolation of seven new triterpenes, six oleane types ( 5, 7 – 11 ) and a new lupane type ( 12 ), and of the six known analogues 1 – 4, 6 , and 13 . The structures and relative configurations of these compounds were elucidated by spectroscopic analyses, including 1D‐ and 2D‐NMR spectroscopy and mass spectrometry, and by the comparison of their NMR data with those of related compounds.

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