Three Tyrosinase Inhibitors and Antioxidant Compounds from Salsola foetida

2003/02/01 by Khalid Mohammed Khan, Khalid Mohammed Khan, Ghulam Murtaza Maharvi +11 · 6 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Antioxidant #Biochemistry #Chemistry #DPPH #Enzyme #Free Radicals and Antioxidants #Organic chemistry #Phytochemical #Phytochemicals and Antioxidant Activities #Stereochemistry #Traditional medicine #Tyrosinase #melanin and skin pigmentation

paper · doi:10.1002/hlca.200390045

openalex publication_date 2003/02/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29

Abstract

Abstract Phytochemical investigation on the whole plant of Salsola foetida resulted in the isolation of three new phenolic compounds 1, 2 , and 3 , which exhibit tyrosinase inhibition with moderate antioxidant activity. Compounds 1 – 3 inhibited tyrosinase with IC 50 2.61, 1.85, and 0.40 μ M , while exhibiting DPPH radical scavenging activity with IC 50 383, 427 and 378 μ M , respectively. The structures of 1, 2 , and 3 were determined by modern spectroscopic techniques.

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