2026/05/14 by Amy Ho, Yann‐Fuu Kou, Christopher Liu +7 · 1 voice
Medicine · Neuroscience · #Neuroscience of respiration and sleep #Obstructive Sleep Apnea Research #Tracheal and airway disorders
paper · doi:10.1002/lary.70629
openalex publication_date 2026/05/14 · openalex created_date 2026/05/16 · openalex updated_date 2026/06/18
ABSTRACT Objective Current guidelines recommend overnight admission for children with severe obstructive sleep apnea (OSA) and obesity undergoing tonsillectomy, although most have uneventful postoperative courses. We aimed to identify low‐risk subgroups within this high‐risk population who may be candidates for same‐day discharge. Methods Retrospective cohort study of children aged 2–18 years with obesity (≥ 95th BMI percentile) and severe OSA ( AHI ≥ 10 events/h and/or SpO 2 nadir < 80%) undergoing tonsillectomy at a tertiary children's hospital (2021–2024). The primary outcome was a severe perioperative event: ICU admission, prolonged hospitalization (> 48 h), or need for advanced respiratory support. Bayesian logistic regression using informative priors identified predictors. Model‐based risk stratification and simplified clinical rules were evaluated using sensitivity, specificity, and negative predictive value. Results Among 304 children, 36 (11.8%) experienced a severe event. SpO 2 nadir was the strongest predictor ( β = −0.668, 95% CrI [−1.164, −0.172], directional probability 99.6%), followed by Class III obesity (97.0%) and AHI (95.0%). Model‐derived stratification identified 33% of patients with < 5% predicted probability of severe events. A clinical rule combining AHI < 25 events/h and SpO 2 nadir > 85% showed sensitivity 85.7% and negative predictive value 99.5%, corresponding to an observed event rate < 5%. Conclusion Most obese children with severe OSA do not experience severe perioperative events. Simple polysomnographic criteria can identify very low‐risk patients who may be candidates for same‐day discharge planning. These findings support a more individualized approach to postoperative admission; prospective validation is needed before implementation. Level of Evidence 4.