Structural insights into <i>ortho</i> -aminophenol oxidases: kinetic and crystallographic characterization of <i>Sm</i> NspF and <i>Sg</i> GriF

2026/01/01 by Hoa Le Xuan, Annette Rompel · 1 voice
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Chemistry · #Enzyme-mediated dye degradation #Metal-Catalyzed Oxygenation Mechanisms #Microbial metabolism and enzyme function

paper · pdf · doi:10.1039/d5qi02495a

openalex publication_date 2026/01/01 · openalex created_date 2026/02/01 · openalex updated_date 2026/08/01

Abstract

-phenylenediamine, which underlies the high versatility of the binuclear copper center. Altogether, these findings provide a structural basis for AO's enzymatic activity and broaden the known catalytic spectrum, which enables the prediction of catalytic properties in type-III copper proteins based on their amino acid sequence.

Citations

• Coupled binuclear copper sites in biology: An experimentally-calibrated computational perspective
• <scp>UCSF ChimeraX</scp>: Tools for structure building and analysis
• КОМПЬЮТЕРНАЯ ТОМОГРАФИЯ – ОСНОВА ОПТИМИЗАЦИИ МИНИТОРАКОТОМНОГО ДОСТУПА
• Highly accurate protein structure prediction with AlphaFold
• UniProt: the universal protein knowledgebase in 2021

Discussions

• 🔔 Hot article by Annette Rompel 𝘦𝘵 𝘢𝘭. Structural insights into ortho-aminophenol oxidases: kinetic and crystallographic characterization of SmNspF and SgGriF 🔗 doi.org/10.1039/D5QI... #Inorg [bsky, 0 points, 0 comments]

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