1999/09/01 by Misael Chinchilla · 1 voice
Medicine · Immunology and Microbiology · #Research on Leishmaniasis Studies #Trypanosoma species research and implications #Parasites and Host Interactions
paper · doi:10.1086/598653
openalex publication_date 1999/09/01 · openalex created_date 2016/06/24 · openalex updated_date 2025/11/06
We describe a 15-month-old eutrophic immunocompetent male who presented with fever, hepatosplenomegaly, pancytopenia, and hypergammaglobulinemia. Leishmania amastigotes were identified in spleen and bone marrow specimens. In addition, tissue culture, animal inoculation, and isoenzyme analysis identified the parasite as Leishmania donovani infantum or Leishmania donovani chagasi. The infant was successfully treated with an antimonial drug. These findings represent the first case of visceral leishmaniasis reported in Costa Rica.