2024/12/30 by Khalsi F ., Belhadj I ., Ben Romdhan M . +4
#Asthma #Asthma control #Asthme #Children #Contrôle de l’asthme #Enfant #Vitamine D #vitamin D
paper · doi:10.71566/pist-rmp-194606
Childhood asthma is a chronic multifactorial inflammatory disorder. It has been described that vitamin D could improve the control of this disorder. The aim of our study was to determine the level of vitamin D status in children with asthma and to analyze the relationship between vitamin D levels and asthma control. Methods : We conduct a descriptive and analytic study in the infantile Medicine B Department of the Child ren's Hospital of Tunis from March 2019 to July 2019. Results : We collected 49 patients with an average age of 7. 6 ± 1. 5 years. Exposure to passive smoking and humidity were reported in 46% and 40% of cases, respectively. Solar exposure was reported in 91% and a high level of pollution was noted in 87% of cases. Obesity was noted in 3 cases. The mean age of diagnosis was 3. 1 years. Asthma was associated with allergic rhinitis in 19 cases. Inhaled corticosteroid therapy (IC) was prescri bed in all cases. Asthma was well controlled in 32 patients. The mean serum 25 (OH) D level was 17. 5 ng / ml . Thirty-three children were deficient in vitamin D. No significant association was found between vitamin D le vels and gender, age, or body mass index. A statistically significant relationship (p = 0. 04) was found between vitamin D levels in subjects not exposed to tobacco compared to those exposed (p = 0. 04). Furthermore, we did not find a correlation between hypovitaminosis D and severe asthma or poor control. Conclusions : Paradoxically, hypovitaminosis D is common in our children with asthma. A large study is recom mended to achieve the role of vitamin d in improving the outcome of this disease.