2023/10/14 by Pao‐Yuan Hsiao, Cyong-Yu Zeng, Ming‐Che Shih · 1 voice · 2 citations
Agricultural and Biological Sciences · Environmental Science · #Coastal wetland ecosystem dynamics #Plant Stress Responses and Tolerance #Plant responses to water stress
paper · pdf · doi:10.1093/plphys/kiad547
openalex publication_date 2023/10/14 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/18
Group VII ethylene response factors (ERFVIIs), whose stability is oxygen concentration-dependent, play key roles in regulating hypoxia response genes in Arabidopsis (Arabidopsis thaliana) and rice (Oryza sativa) during submergence. To understand the evolution of flooding tolerance in cereal crops, we evaluated whether Brachypodium distachyon ERFVII genes (BdERFVIIs) are related to submergence tolerance. We found that three BdERFVIIs, BdERF108, BdERF018, and BdERF961, form a feedback regulatory loop to mediate downstream responses. BdERF108 and BdERF018 activated the expression of BdERF961 and PHYTOGLOBIN 1 (PGB1), which promoted nitric oxide turnover and preserved ERFVII protein stability. The activation of PGB1 was subsequently counteracted by increased BdERF961 accumulation through negative feedback regulation. Interestingly, we found that OsERF67, the orthologue of BdERF961 in rice, activated PHYTOGLOBIN (OsHB2) expression and formed distinct regulatory loops during submergence. Overall, the divergent regulatory mechanisms exhibited by orthologs collectively offer perspectives for the development of submergence-tolerant crops.