2021/02/07 by John P. Efromson, Shuai Li, Michael Lynch · 1 voice · 1 citation
Engineering · #Innovative Microfluidic and Catalytic Techniques Innovation #Microfluidic and Bio-sensing Technologies #Microfluidic and Capillary Electrophoresis Applications
paper · doi:10.1016/j.ohx.2021.e00177
openalex publication_date 2021/02/07 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
Autosampling from bioreactors reduces error, increases reproducibility and offers improved aseptic handling when compared to manual sampling. Additionally, autosampling greatly decreases the hands-on time required for a bioreactor experiment and enables sampling 24 h a day. We have designed, built and tested a low cost, open source, automated bioreactor sampling system, the BioSamplr. The BioSamplr can take up to ten samples from a bioreactor at a desired sample interval and cools them to a desired temperature. The device, assembled from low cost and 3D printed components, is controlled wirelessly by a Raspberry Pi, and records all sampling data to a log file. The cost and accessibility of the BioSamplr make it useful for laboratories without access to more expensive and complex autosampling systems.