2021/12/20 by Rafael Gómez-Sjöberg, Joana P. Cabrera, Andrew Cote · 1 voice
Biochemistry, Genetics and Molecular Biology · Engineering · #Biosensors and Analytical Detection #Genetics, Bioinformatics, and Biomedical Research #Microfluidic and Capillary Electrophoresis Applications
paper · doi:10.1101/2021.12.17.473010
openalex publication_date 2021/12/20 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/14
Abstract A very large number of biology and biochemistry laboratory protocols require transferring liquid aliquots from individual containers into individual wells of a multi-well plate, from plates to individual containers, or from one plate to another. Doing this by hand without errors, such as skipping wells, placing two samples in the same well, or swapping sample locations, especially when using plates with 96 wells or more, is difficult and requires enormous operator focus and/or a tedious manual error checking system. We present here a device built to facilitate error-free pipetting of samples from individual barcoded tubes to a multi-well plate or between multi-well plates (both 96 and 384 wells are supported). The device is programmable, modular and easily customizable to accommodate plates with different form-factors, and different protocols. The main components are only a 12.3” touch screen, a small form-factor PC, and a barcode scanner, combined with custom-made parts can be easily fabricated with a laser cutter and a hobby-grade 3D printer. The total cost is between approximately US550 and US600, depending on the configuration. Specifications table