Geometric effects of volume-to-surface mapping of fMRI data

2022/07/27 by Keith George Ciantar, Christine Farrugia, Paola Galdi +3 · 1 voice
Neuroscience · Medicine · #Functional Brain Connectivity Studies #Advanced Neuroimaging Techniques and Applications #Advanced MRI Techniques and Applications

paper · pdf · doi:10.1007/s00429-022-02536-4

openalex publication_date 2022/07/27 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/31

Abstract

In this work, we identify a problem with the process of volume-to-surface mapping of functional Magnetic Resonance Imaging (fMRI) data that emerges in local connectivity analysis. We show that neighborhood correlations on the surface of the brain vary spatially with the gyral structure, even when the underlying volumetric data are uncorrelated noise. This could potentially have impacted studies focusing upon local neighborhood connectivity. We explore the effects of this anomaly across varying data resolutions and surface mesh densities, and propose several measures to mitigate these unwanted effects.

Discussions

• Our functional connectivity was inspired by Ciantar et al. (2022) doi.org/10.1007/s004... which was recently replicated by Jeganathan et al. www.biorxiv.org/content/10.1... See also related work on vo [bsky, 1 points, 0 comments]

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