Carbene transfer reactivity from a nickelacyclobutane

2024/01/01 by María L. G. Sansores‐Paredes, Martin Lutz, Marc‐Etienne Moret · 1 voice
Chemistry · #Cyclopropane Reaction Mechanisms #Asymmetric Hydrogenation and Catalysis #Organometallic Complex Synthesis and Catalysis

paper · pdf · doi:10.1039/d4cc04273e

openalex publication_date 2024/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/31

Abstract

A formal carbene-transfer reaction from an isolated nickelacyclobutane to an isocyanide to form a ketenimine is reported. DFT calculations support a stepwise 1,1-insertion/fragmentation pathway without a carbene intermediate. This unusual reactivity suggests a potential new role as "carbene reservoir" for nickelacyclobutanes, which are typically seen as intermediates in catalytic cyclopropanation.

Discussions

• Then, an unusual carbene transfer reaction to an isocyanide ligand was uncovered: doi.org/10.1039/D4CC... 3/3 [bsky, 1 points, 0 comments]

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