2025/02/12 by Clémence Gandaux, Jérôme Sallet, Céline Amiez +11 · 1 voice
Neuroscience · #Neural and Behavioral Psychology Studies #Memory and Neural Mechanisms #Mind wandering and attention
paper · pdf · doi:10.1101/2025.02.11.637635
openalex publication_date 2025/02/12 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
Abstract The neuronal connections between the midcingulate cortex (MCC) and the dorsolateral prefrontal cortex (dlPFC) are associated with multiple cognitive functions, including rapid and long-term adaptive processes. Here we show that DREADD-mediated activation of MCC to dlPFC projection in macaques led to increased engagement in a foraging task, but did not alter their trial-to-trial adaptive strategy. We conclude that a critical role for MCC-dlPFC pathway is in the temporally extended control of behaviour rather than in rapid adaptation.