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A closer look at Doleac and Mukherjee (2022) and the effects of naloxone access laws on opioid ER admissions

2025/03/09 by Sergey Alexeev · 1 voice · 1 citation
Medicine · #Opioid Use Disorder Treatment #Cardiac Arrest and Resuscitation #Pharmaceutical Practices and Patient Outcomes

paper · doi:10.1111/ecin.13277

openalex publication_date 2025/03/09 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/27

Abstract

Abstract In their 2022 study, ‘The Effects of Naloxone Access Laws on Opioid Abuse, Mortality, and Crime,’ Doleac and Mukherjee conclude that broadening access to a life‐saving drug—naloxone—does not reduce opioid‐related mortality as the drug simultaneously encourages riskier drug use. I show issues with their data, design, and estimation methods. For example, their Google Search data has an unverifiable origin, the law timing is incorrect, and the statistical inference is invalid. Correcting these issues within a triple difference design shows that naloxone, contrary to their findings, does not increase ER opioid admissions. I conclude that the moral hazard (and the ensuing adverse consequences) of naloxone use lacks empirical support.

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