Replacement of hydrogen by halogen bonds within nucleic acid base pairs

2025/01/01 by Akhtam Amonov, Steve Scheiner · 1 voice
Pharmacology, Toxicology and Pharmaceutics · #Fluorine in Organic Chemistry

paper · doi:10.1039/d5nj00977d

openalex publication_date 2025/01/01 · openalex created_date 2025/03/26 · openalex updated_date 2026/07/28

Abstract

Quantum calculations show that replacement of the H-bonds within DNA base pairs by halogen bonds can enhance their binding to one another.

Citations

• Definition of the hydrogen bond (IUPAC Recommendations 2011)
• The calculation of small molecular interactions by the differences of separate total energies. Some procedures with reduced errors
• P SI4 1.4: Open-source software for high-throughput quantum chemistry

Discussions

• Issue 16 is now online. The cover features work by Akhtam Amonov and Steve Scheiner on 'Replacement of hydrogen by halogen bonds within nucleic acid base pairs' doi.org/10.1039/D5NJ... #Chemsky [bsky, 1 points, 0 comments]

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