The early years of lipoprotein research: from discovery to clinical application

2016/07/30 by Patty W. Siri‐Tarino, Ronald M. Krauss · 1 voice
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Atherosclerosis and Cardiovascular Diseases #Cancer, Lipids, and Metabolism #Lipoproteins and Cardiovascular Health

paper · pdf · doi:10.1194/jlr.r069575

openalex publication_date 2016/07/30 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

This review outlines major milestones in the first four decades of lipoprotein research beginning with their discovery nearly 90 years ago. It focuses on the contributions of some of the key investigators during this era, and findings that set the stage for widespread clinical implementation of lipoprotein testing for evaluation and management of CVD risk.

Citations

• Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge

Discussions

• From medicine, the first method to measure lipid levels in blood (LDLs etc) was initially rejected by Journal of Biological Chemistry in 1949: doi.org/10.1194/jlr.... [bsky, 1 points, 0 comments]

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