2025/06/09 by Anastasios Charalampidis, Elias Diarbakerli, Kourosh Jalalpour +5 · 1 voice
Medicine · #Scoliosis diagnosis and treatment #Spinal Fractures and Fixation Techniques #Hip disorders and treatments
paper · pdf · doi:10.2340/17453674.2025.43706
openalex publication_date 2025/06/09 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
BACKGROUND AND PURPOSE: Data on effectiveness of nighttime bracing compared with full-time bracing in adolescent idiopathic scoliosis is scarce. We aimed to investigate risk of curve progression and surgery with nighttime bracing vs full-time bracing for patients with moderate-grade adolescent idiopathic scoliosis. METHODS: Skeletally immature individuals with idiopathic scoliosis (25°-40°) treated with a nighttime brace as part of a parallel-group randomized controlled trial (RCT) were compared with non-participants treated with a full-time brace. In the case of curve progression of more than 6° in the nighttime brace group individuals were offered transition to a full-time brace. Surgery was offered if curve sizes were 45° or larger. RESULTS: Median age at treatment start was 12.8 years (nighttime brace n = 45, full-time brace n = 44). Female sex (odds ratio [OR] 6.5, 95% confidence interval [CI] 1.1-37.4), lower Risser grade (OR 1.6, CI 1.01-2.7), and larger curve size at the beginning of brace treatment (OR 1.4, CI 1.2-1.5) increased the risk of curve progression to ≥ 45°. Major curves in the groups were similar at median 33 months' follow-up (P = 0.7). After 94 months of follow-up, 11 patients in the nighttime brace group and 6 in the full-time brace group had undergone surgery (OR 2.0, CI 0.7-6.1). CONCLUSION: Nighttime bracing, including a possibility to transition to full-time brace in the case of progression, demonstrated comparable effectiveness in preventing curve progression, but a tendency to a higher risk of surgical treatment.