Magnetic hyperthermia-triggered multi-functional thermo-responsive lipid nanoparticles for enhanced paclitaxel release and cytotoxicity

2025/01/01 by Muhammad Tayyab, Naveed Ahmed, Muhammad Hisham Al Nasir +6 · 1 voice
Biochemistry, Genetics and Molecular Biology · Materials Science · Pharmacology, Toxicology and Pharmaceutics · #Advancements in Transdermal Drug Delivery #Lipid Membrane Structure and Behavior #Nanoparticle-Based Drug Delivery

paper · pdf · doi:10.1039/d5na00072f

openalex publication_date 2025/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/06/25

Abstract

and TLNs exhibited high biocompatibility, but TLN encapsulation significantly improved uptake in MCF-7 breast cancer cells. Under AMF, P-γ-TLN showed enhanced PTX release, resulting in more potent cytotoxicity against MCF-7 cells. The combination of high payload capacity, stimuli-responsive release, thermotherapy, and enhanced chemotherapeutic response highlights the substantial potential for TLNs in cancer therapy.

Citations

• Preparation of aqueous magnetic liquids in alkaline and acidic media

Discussions

• Nanoscale Advances issue 13 is out now! Featuring this cover article by Naveed Ahmed, Daniel Jaque Garcia, Mubashar Rehman et al. on 'Magnetic hyperthermia-triggered multi-functional thermo-responsive [bsky, 1 points, 0 comments]

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