Unravelling the synergies: effects of hydrogel mechanics and biofunctionalization on mesenchymal stem cell osteogenic differentiation

2025/01/01 by Cristina López-Serrano, Murielle Rémy, Thierry Lesté-Lasserre +2 · 1 voice
Biochemistry, Genetics and Molecular Biology · Medicine · #Cellular Mechanics and Interactions #Connective tissue disorders research #Tissue Engineering and Regenerative Medicine

paper · pdf · doi:10.1039/d5ma00165j

openalex publication_date 2025/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/22

Abstract

Viscoelastic properties as well as peptide functionalization of PEGDA hydrogels affect cell differentiation towards the osteogenic lineage.

Citations

• Mind the Viscous Modulus: The Mechanotransductive Response to the Viscous Nature of Isoelastic Matrices Regulates Stem Cell Chondrogenesis

Discussions

• Materials Advances issue 14 is out now! Featuring this cover article by Gaétan Laroche, Marie-Christine Durrieu et al. on 'Unravelling the synergies: effects of hydrogel mechanics and biofunctionaliza [bsky, 1 points, 0 comments]

Related

• Mind the Viscous Modulus: The Mechanotransductive Response to the Viscous Nature of Isoelastic Matrices Regulates Stem Cell Chondrogenesis
• Current hydrogel advances in physicochemical and biological response-driven biomedical application diversity
• Influence of viscosity on adipogenic and osteogenic differentiation of mesenchymal stem cells during 2D culture
• Mechanical regulation of mesenchymal stem cell differentiation
• Collagen-hyaluronic acid hydrogel with embedded chondrocytes as a platform for modeling early stages of endochondral ossification in vitro