2025/07/21 by Simone Adorinni, Silvia Marchesan · 1 voice
Materials Science · #Diatoms and Algae Research #Nanocluster Synthesis and Applications #Supramolecular Self-Assembly in Materials
paper · doi:10.1002/cbic.202500351
openalex publication_date 2025/07/21 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/23
Peptide-based supramolecular assemblies have emerged as useful scaffolds to control the synthesis and spatial organization of gold nanoparticles (AuNPs) into nanocomposite superstructures. This concept article summarizes recent progress in the design of peptide-directed AuNP assemblies, focusing on how subtle variations in peptide sequence, conjugation strategy, and synthesis conditions influence NP morphology, chiral arrangement, and the resulting optical properties. It highlights key strategies for rationally tailoring structural parameters, such as particle size, shape, and interparticle spacing, which determine the collective optical and plasmonic behaviors of the assemblies. The fundamental design rules discussed here provide critical insights for constructing programmable AuNP-based nanomaterials, potentially useful in diverse fields including sensing, optical devices, and catalysis. Finally, it outlines current challenges and propose directions to further exploit the unique versatility of peptide-nanoparticle hybrid systems in nanotechnology.