2025/01/01 by Mercedes Novo, Sara Illodo, Juan Seijas +3 · 1 voice
Materials Science · Neuroscience · #Luminescence and Fluorescent Materials #Photoreceptor and optogenetics research #Supramolecular Self-Assembly in Materials
paper · pdf · doi:10.1039/d5cp01547b
openalex publication_date 2025/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01
= 19 μM, distinct aggregation behaviours are observed. By employing steady-state fluorescence spectroscopy, a widely accessible technique, these findings establish a direct link between early Aβ aggregation and intrinsic fluorescence changes. This approach eliminates the need for extrinsic probes, simplifying experimental procedures and reducing artefacts. Although further studies are required to develop a robust quantitative correlation for potential diagnostic applications, Aβ autofluorescence represents a promising strategy for investigating early aggregation processes in the context of AD.