LINC01638 promotes epithelial-to-mesenchymal transition in endometriosis epithelial cells by up-regulating RHOB via HDAC1 suppression

2025/03/14 by Iveta Yotova, Katharina Proestling, Florian M. Pauler +7 · 1 voice · 1 citation
Chemistry · Immunology and Microbiology · Medicine · #Biology #Cancer research #Cell biology #Chemistry #Endometriosis #Endometriosis Research and Treatment #Epithelial–mesenchymal transition #Gene #Gynecological conditions and treatments #HDAC1 #Histone #Histone deacetylase #Medicine #Pathology #RHOB #Reproductive System and Pregnancy #Signal transduction #Transition (genetics)

paper · doi:10.1016/j.rbmo.2025.104942

published in Reproductive BioMedicine Online 51(3), 104942 (Elsevier BV)

openalex publication_date 2025/03/14 · crossref created 2025/03/14 · crossref deposited 2025/08/20 · crossref issued 2025/09/01 · crossref published 2025/09/01 · crossref published-print 2025/09/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/06/15 · crossref indexed 2026/07/19

Citations

• The basics of epithelial-mesenchymal transition
• Systematic risk behavior of financially distressed firms
• Long non-coding RNAs: definitions, functions, challenges and recommendations
• Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Discussions

• In the pathogenesis of endometriosis, LINC01638 may act as a chromatin remodeller by modulating the levels of expression of HDAC1 to induce partial EMT in endometriotic lesions. RBMO subscribers can [bsky, 1 points, 0 comments]