Pirin, a redox-sensitive modulator of beta-oxidation, generates hydroxyl radicals and interacts with CatR, the transcriptional repressor of the major vegetative catalase gene in Streptomyces

2025/08/13 by Matteo Calcagnile, Fabrizio Damiano, Adelfia Talà +1 · 1 voice
Agricultural and Biological Sciences · Chemistry · Environmental Science · #Enzyme-mediated dye degradation #Metal-Catalyzed Oxygenation Mechanisms #Microbial bioremediation and biosurfactants

paper · doi:10.1016/j.micres.2025.128310

openalex publication_date 2025/08/13 · openalex created_date 2025/10/10 · openalex updated_date 2026/06/26

Abstract

exposure, PirA could promote CatR inactivation allowing catA transcription.

Citations

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Discussions

• We found that Pirin, a redox-sensitive modulator of β-oxidation in Streptomyces, generates radicals as a signal to activate antioxidant systems and interacts with CatR, the repressor of catalase Evol [bsky, 1 points, 0 comments]

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