Vaccine effectiveness against SARS-CoV-2 transmission to household contacts during dominance of Delta variant (B.1.617.2), the Netherlands, August to September 2021

2021/11/04 by Brechje de Gier, Stijn P. Andeweg, Jantien A. Backer +5 · 1 voice · 1 citation
Medicine · Social Sciences · Mathematics · #SARS-CoV-2 and COVID-19 Research #Vaccine Coverage and Hesitancy #COVID-19 epidemiological studies

paper · pdf · doi:10.2807/1560-7917.es.2021.26.44.2100977

openalex publication_date 2021/11/04 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/02

Abstract

We estimated SARS-CoV-2 vaccine effectiveness against onward transmission by comparing secondary attack rates among household members for vaccinated and unvaccinated index cases, based on source and contact tracing data collected when the Delta variant was dominant. Effectiveness of full vaccination of the index case against transmission to unvaccinated and fully vaccinated household contacts, respectively, was 63% (95% confidence interval (CI): 46-75) and 40% (95% CI: 20-54), in addition to the direct protection of vaccination of contacts against infection.

Cited by

• Effect of vaccination on household transmission of SARS-CoV-2 Delta variant of concern

Discussions

• Various studies also estimated VE against transmission in breakthrough infections. This contact tracing study in the Netherlands estimated this to be 63% [46%, 75%] for unvaccinated contacts, and 40 [bsky, 1 points, 1 comments]

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